Andrianov et al., 1998 - Google Patents
Protein release from polyphosphazene matricesAndrianov et al., 1998
- Document ID
- 3573892170239698210
- Author
- Andrianov A
- Payne L
- Publication year
- Publication venue
- Advanced drug delivery reviews
External Links
Snippet
Polyphosphazenes have been exploited as carriers for protein delivery due to versatility of molecular structures and sophisticated spectrum of chemical and physical properties. Ease of structural manipulations for this class of organometallic polymers allows efficient control …
- 229920002627 poly(phosphazenes) 0 title abstract description 95
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
- A61K47/30—Macromolecular compounds
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Andrianov et al. | Protein release from polyphosphazene matrices | |
| KR100353496B1 (en) | Hydrogel Microencapsulated Vaccine | |
| Andrianov et al. | Polymeric carriers for oral uptake of microparticulates | |
| Akhtar et al. | Methods of synthesis of hydrogels… A review | |
| Heller et al. | Controlled release of water-soluble macromolecules from bioerodible hydrogels | |
| Andrianov et al. | Synthesis and biologically relevant properties of polyphosphazene polyacids | |
| Lakshmi et al. | Biodegradable polyphosphazenes for drug delivery applications | |
| AU690567B2 (en) | Hydrogel microencapsulated vaccines | |
| Chaubal et al. | Polyphosphates and other phosphorus-containing polymers for drug delivery applications | |
| US20040258753A1 (en) | Pulsed bio-agent delivery systems based on degradable polymer solutions or hydrogels | |
| Andrianov | Water-soluble polyphosphazenes for biomedical applications | |
| US6207171B1 (en) | Polyphosphazene microspheres | |
| US5807757A (en) | Preparation of ionically cross-linked polyphosphazene microspheresy by coacervation | |
| WO1995002416A9 (en) | Hydrogel microencapsulated vaccines | |
| CA2424936A1 (en) | Vaccine composition comprising an immunologically active substance embedded in microparticles consisting of starch with reduced molecular weight | |
| Sharma et al. | Hydrogels: from simple networks to smart materials—advances and applications | |
| Lee et al. | Surface perspectives in the biomedical applications of poly (α-hydroxy acid) s and their associated copolymers | |
| Andrianov et al. | Polyphosphazene hydrogel microspheres for protein delivery | |
| Ilia | Phosphorus containing hydrogels | |
| Khan et al. | Poly (organo) phosphazenes: recent progress in the synthesis and applications in tissue engineering and drug delivery | |
| Andrianov | Polyphosphazenes as vaccine adjuvants | |
| AU2005267536B2 (en) | Injectable microspheres from unsaturated functionalized polyhydric alcohol esters | |
| Dinarvand et al. | Polymeric delivery systems for biopharmaceuticals | |
| Semwal et al. | Drug delivery systems: selection criteria and use | |
| Hydrogel et al. | I. POLYORGANOPHOSPHAZENE HYDROGELS AS MATRICES FOR DRUG DELIVERY |