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Nejadnik et al., 2015 - Google Patents

Improved approach for chondrogenic differentiation of human induced pluripotent stem cells

Nejadnik et al., 2015

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Document ID
3389456022438006976
Author
Nejadnik H
Diecke S
Lenkov O
Chapelin F
Donig J
Tong X
Derugin N
Chan R
Gaur A
Yang F
Wu J
Daldrup-Link H
Publication year
Publication venue
Stem Cell Reviews and Reports

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Snippet

Human induced pluripotent stem cells (hiPSCs) have demonstrated great potential for hyaline cartilage regeneration. However, current approaches for chondrogenic differentiation of hiPSCs are complicated and inefficient primarily due to intermediate …
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
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    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
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    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
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