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Lee et al., 2004 - Google Patents

Control of HIV-1 replication by RNA interference

Lee et al., 2004

Document ID
3136448487118525357
Author
Lee N
Rossi J
Publication year
Publication venue
Virus research

External Links

Snippet

Small interfering RNAs (siRNAs) have been shown to direct sequence-specific inhibition of gene expression in mammalian cells. siRNAs are RNA duplexes of 21–23 nucleotides (nts) with∼ 2nt 3′ overhangs that can induce degradation of their homologous target mRNAs …
Continue reading at www.sciencedirect.com (other versions)

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    • C12N15/1132—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against retroviridae, e.g. HIV
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