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Hayes, 2004 - Google Patents

The use of 4‐aminopyridine (fampridine) in demyelinating disorders

Hayes, 2004

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Document ID
270895485437226786
Author
Hayes K
Publication year
Publication venue
CNS drug reviews

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Snippet

Aminopyridine (4‐AP or fampridine) is a potassium channel‐blocking agent that has been shown to restore conduction in focally demyelinated axons. A sustained‐release matrix tablet form of 4‐AP (fampridine‐SR) is currently undergoing multicenter clinical trials in …
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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