[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Lenigk et al., 2002 - Google Patents

Plastic biochannel hybridization devices: a new concept for microfluidic DNA arrays

Lenigk et al., 2002

View PDF
Document ID
2618690755577192299
Author
Lenigk R
Liu R
Athavale M
Chen Z
Ganser D
Yang J
Rauch C
Liu Y
Chan B
Yu H
Ray M
Marrero R
Grodzinski P
Publication year
Publication venue
Analytical biochemistry

External Links

Snippet

Conventional DNA hybridization assay kinetics depends solely on the diffusion of target to surface-bound probes, causing long hybridization times. In this study, we examined the possibilities of accelerating the hybridization process by using microfluidic channels …
Continue reading at www.academia.edu (PDF) (other versions)

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B01J2219/00317—Microwell devices, i.e. having large numbers of wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical, or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes

Similar Documents

Publication Publication Date Title
Lenigk et al. Plastic biochannel hybridization devices: a new concept for microfluidic DNA arrays
Situma et al. Merging microfluidics with microarray-based bioassays
Ali et al. DNA hybridization and discrimination of single-nucleotide mismatches using chip-based microbead arrays
Nagai et al. Development of a microchamber array for picoliter PCR
Dufva Fabrication of high quality microarrays
Liu et al. DNA probe attachment on plastic surfaces and microfluidic hybridization array channel devices with sample oscillation
Boles et al. Droplet-based pyrosequencing using digital microfluidics
Gabig et al. An introduction to DNA chips: principles, technology, applications and analysis
Situma et al. Fabrication of DNA microarrays onto poly (methyl methacrylate) with ultraviolet patterning and microfluidics for the detection of low-abundant point mutations
Sanders et al. Chip-based microsystems for genomic and proteomic analysis
Kricka Miniaturization of analytical systems
US7238323B2 (en) Microfluidic sequencing systems
US6780584B1 (en) Electronic systems and component devices for macroscopic and microscopic molecular biological reactions, analyses and diagnostics
US20020058329A1 (en) Multiple-site reaction device and method
Dufva Introduction to microarray technology
EP1288666A2 (en) Apparatus and method for simultaneously conducting multiple chemical reactions
Henry et al. Rapid DNA hybridization in microfluidics
Wang et al. Fungal pathogenic nucleic acid detection achieved with a microfluidic microarray device
Köhler et al. Chip devices for miniaturized biotechnology
US20040043494A1 (en) Apparatus for studying arrays
Bromberg et al. Microfabricated linear hydrogel microarray for single-nucleotide polymorphism detection
Ng et al. Miniaturized platforms for the detection of single-nucleotide polymorphisms
Ng et al. Rapid discrimination of single-nucleotide mismatches using a microfluidic device with monolayered beads
Abramowitz DNA analysis in microfabricated formats
Obeid et al. Microfabricated systems for nucleic acid analysis