[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Nagano et al., 2007 - Google Patents

Synthesis of Unsymmetrically and Highly Substituted Thiophenes Utilizing Regioselective Ring-expansion of gem-Dichlorocyclopropyl Ketones with Lawesson's …

Nagano et al., 2007

Document ID
2544436849304857237
Author
Nagano T
Kimoto H
Nakatsuji H
Motoyoshiya J
Aoyama H
Tanabe Y
Nishii Y
Publication year
Publication venue
Chemistry letters

External Links

Snippet

Ring-expansion of aryl gem-dichlorocyclopropyl ketones 1 using Lawesson's reagent afforded unsymmetrically and highly substituted 5-chloro and 3-chlorothiophenes 2 and 3 with excellent regioselectivity. The Suzuki–Miyaura coupling of 2 and 3 with PhB (OH) 2 was …
Continue reading at academic.oup.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58—One oxygen atom, e.g. butenolide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulfur
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulfur with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/307—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2101/00—Systems containing only non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM

Similar Documents

Publication Publication Date Title
Hussain et al. Site-selective Suzuki–Miyaura reactions of 2, 3-dibromo-1H-inden-1-one
Wu et al. Cu-Mediated arylselenylation of aryl halides with trifluoromethyl aryl selenonium ylides
KR101728443B1 (en) Method for Producing Benzyl Ester 2-aminonicotinicotinate Derivative
Nagano et al. Synthesis of Unsymmetrically and Highly Substituted Thiophenes Utilizing Regioselective Ring-expansion of gem-Dichlorocyclopropyl Ketones with Lawesson’s Reagent
Chackal-Catoen et al. Dicationic DNA-targeted antiprotozoal agents: naphthalene replacement of benzimidazole
Li et al. PhI (OAc) 2-mediated additions of 2, 4-dinitrophenylsulfenamide with methylenecyclopropanes (MCPs) and a methylenecyclobutane (MCB)
Akiyama et al. Stereoselective synthesis of cyclopentanols by Lewis acid-mediated [3+ 2] annulation of allyldiisopropylphenylsilane with α, β-unsaturated diesters
US6313320B1 (en) Process for the preparation of calanolide precursors
Lewandowska Nucleophilic α-addition to β-nitroacrylates: application to the synthesis of α-thioacrylates
KR101603324B1 (en) Method for preparation of 3-alkylthio-2-bromopyridine
KR101623810B1 (en) Synthesis of furan, thiophene, and pyrroles from acetoacetic esters
WO2008152217A2 (en) Process for preparing 2-(n-butyl)-5-nitrobenzofuran
Rosa et al. Total synthesis of smenochromene B through ring contraction
Toyota et al. Unexpected formation of 4, 7-dihalobenzo [b] thiophenes using Ohira-Bestmann reagent and reactivity of the halogen-substituted benzo [b] thiophenes in Suzuki-Miyaura coupling with phenylboronic acid
Park et al. Synthesis of benzo [1, 2-b: 4, 5-b′] difuran derivatives utilizing concomitant photocyclization and photo-Fries rearrangement reactions
Tatsugi et al. A Facile Synthesis of 1-Alkyl-7-azalsatins
CN111527072A (en) Method for producing herbicidal pyridazinone compound
FR2914643A1 (en) PROCESS FOR THE PREPARATION OF 2- (N-BUTYL) -5-NITROBENZOFURAN
EP2011792A1 (en) 2-alkenyl-3-aminothiophene derivative and method for producing the same
KR100424341B1 (en) A process for preparing 1-Methyl- indazole-3-carboxylic acid
Ono et al. Synthesis and Properties of Monocyclic 5 H-1, 2-Oxathioles (Cyclic α, β-Unsaturated Sulfenic Acid Esters)
CN104961747B (en) A kind of tetrahydro benzo [d] [1,2,6] oxa- phenodiazine * class compounds and preparation method thereof
CN108164435B (en) Green and efficient synthesis method of aryl acrylonitrile compound
KR102477316B1 (en) Method for preparing 4-substituted 2,3-dihydro-1-benzofuran derivatives by ring closure of 2-(2-diazonium-6-substituted phenyl)ethanol salts
CN110914250B (en) Novel process for synthesizing tilobaxib