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Hu et al., 2018 - Google Patents

Stereoisomers of schisandrin B are potent ATP competitive GSK-3β inhibitors with neuroprotective effects against Alzheimer's disease: Stereochemistry and biological …

Hu et al., 2018

Document ID
2230260023471056706
Author
Hu X
Guo C
Hou J
Feng J
Zhang X
Xiong F
Ye W
Wang H
Publication year
Publication venue
ACS Chemical Neuroscience

External Links

Snippet

Glycogen synthase kinase-3β (GSK-3β) is a key enzyme in hyperphosphorylation of tau proteins and is a promising therapeutic target in Alzheimer's disease (AD). Here, we reported, for the first time, that the stereoisomers of Schisandrin B (Sch B),(+)-1,(−)-1,(+)-2 …
Continue reading at pubs.acs.org (other versions)

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    • A61K36/258—Panax (ginseng)
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