Sinha et al., 2009 - Google Patents
Extrusion-spheronization: process variables and characterizationSinha et al., 2009
- Document ID
- 200919677118564190
- Author
- Sinha V
- Agrawal M
- Agarwal A
- Singh G
- Ghai D
- Publication year
- Publication venue
- Critical Reviews™ in Therapeutic Drug Carrier Systems
External Links
Snippet
Multiparticulate systems have undergone great development in the past decade fueled by the better understanding of their multiple roles as a suitable delivery system. With the passage of time, significant advances have been made in the process of pelletization due to …
- 238000005563 spheronization 0 title abstract description 143
Classifications
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
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- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
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