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Jensen et al., 2019 - Google Patents

Heterogeneity spacers in 16S rDNA primers improve analysis of mouse gut microbiomes via greater nucleotide diversity

Jensen et al., 2019

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Document ID
1915347190416865782
Author
Jensen E
Berryman D
Murphy E
Carroll R
Busken J
List E
Broach W
Publication year
Publication venue
Biotechniques

External Links

Snippet

Illumina-based amplicon sequencing suffers from the deleterious effects of highly homogenous nucleotide composition, limiting the number of high-quality reads generated per run. We attempted to alleviate this limitation by comparing the results obtained from 16S …
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    • G06F19/22—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or SNP [Single-Nucleotide Polymorphism] discovery or sequence alignment
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