Dorozhkin, 2019 - Google Patents
Nanometric calcium orthophosphates (CaPO4): Preparation, properties and biomedical applicationsDorozhkin, 2019
View PDF- Document ID
- 1852379238833850675
- Author
- Dorozhkin S
- Publication year
- Publication venue
- Adv Nano Bio M&D
External Links
Snippet
Nanometric particles and crystals play very important roles in biological systems. For example, calcium orthophosphates (abbreviated as CaPO4) of nanometric dimensions represent the basic inorganic building blocks of bones and teeth of mammals. According to …
- QORWJWZARLRLPR-UHFFFAOYSA-H Tricalcium phosphate data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-3 atom-4' d='M 41.7,230.8 L 48.8,226.7' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-3 atom-4' d='M 48.8,226.7 L 55.9,222.6' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-4 atom-5' d='M 63.7,191.6 L 60.8,186.7' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-4 atom-5' d='M 60.8,186.7 L 58.0,181.7' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-4 atom-6' d='M 89.5,236.3 L 92.4,241.4' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-4 atom-6' d='M 92.4,241.4 L 95.3,246.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-4 atom-7' d='M 98.1,205.4 L 105.6,201.1' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-4 atom-7' d='M 105.6,201.1 L 113.0,196.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-4 atom-7' d='M 91.9,194.6 L 99.3,190.3' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-4 atom-7' d='M 99.3,190.3 L 106.8,186.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-8 atom-9' d='M 191.4,230.8 L 198.5,226.7' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-8 atom-9' d='M 198.5,226.7 L 205.6,222.6' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-9 atom-10' d='M 213.4,191.6 L 210.5,186.7' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-9 atom-10' d='M 210.5,186.7 L 207.7,181.7' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-9 atom-11' d='M 239.2,236.3 L 242.1,241.4' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-9 atom-11' d='M 242.1,241.4 L 245.0,246.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-9 atom-12' d='M 247.8,205.4 L 255.3,201.1' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-9 atom-12' d='M 255.3,201.1 L 262.7,196.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-9 atom-12' d='M 241.6,194.6 L 249.0,190.3' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-9 atom-12' d='M 249.0,190.3 L 256.5,186.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='67.7' y='128.3' class='atom-0' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >C</text>
<text x='84.9' y='128.3' class='atom-0' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >a</text>
<text x='98.2' y='118.4' class='atom-0' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >2</text>
<text x='106.2' y='118.4' class='atom-0' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >+</text>
<text x='67.7' y='86.7' class='atom-1' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >C</text>
<text x='84.9' y='86.7' class='atom-1' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >a</text>
<text x='98.2' y='76.8' class='atom-1' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >2</text>
<text x='106.2' y='76.8' class='atom-1' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >+</text>
<text x='67.7' y='45.1' class='atom-2' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >C</text>
<text x='84.9' y='45.1' class='atom-2' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >a</text>
<text x='98.2' y='35.2' class='atom-2' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >2</text>
<text x='106.2' y='35.2' class='atom-2' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >+</text>
<text x='13.6' y='255.2' class='atom-3' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='30.9' y='245.2' class='atom-3' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='67.7' y='224.0' class='atom-4' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#FF60B7' >P</text>
<text x='36.5' y='169.9' class='atom-5' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='53.7' y='160.0' class='atom-5' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='98.9' y='278.0' class='atom-6' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='116.1' y='268.0' class='atom-6' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='121.7' y='192.8' class='atom-7' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='163.3' y='255.2' class='atom-8' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='180.5' y='245.2' class='atom-8' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='217.3' y='224.0' class='atom-9' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#FF60B7' >P</text>
<text x='186.2' y='169.9' class='atom-10' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='203.4' y='160.0' class='atom-10' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='248.5' y='278.0' class='atom-11' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='265.8' y='268.0' class='atom-11' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='271.4' y='192.8' class='atom-12' style='font-size:24px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-3 atom-4' d='M 8.3,66.7 L 13.3,63.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-3 atom-4' d='M 13.3,63.8 L 18.3,60.9' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-4 atom-5' d='M 19.3,56.9 L 16.8,52.4' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-4 atom-5' d='M 16.8,52.4 L 14.2,48.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-4 atom-6' d='M 23.1,63.4 L 25.7,67.8' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-4 atom-6' d='M 25.7,67.8 L 28.2,72.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-4 atom-7' d='M 24.2,59.5 L 29.4,56.5' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-4 atom-7' d='M 29.4,56.5 L 34.5,53.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-4 atom-7' d='M 22.5,56.4 L 27.6,53.5' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-4 atom-7' d='M 27.6,53.5 L 32.7,50.5' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-8 atom-9' d='M 50.7,66.7 L 55.7,63.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-8 atom-9' d='M 55.7,63.8 L 60.7,60.9' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-9 atom-10' d='M 61.7,56.9 L 59.2,52.4' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-9 atom-10' d='M 59.2,52.4 L 56.6,48.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-9 atom-11' d='M 65.5,63.4 L 68.1,67.8' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-9 atom-11' d='M 68.1,67.8 L 70.6,72.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-9 atom-12' d='M 66.7,59.5 L 71.8,56.5' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-9 atom-12' d='M 71.8,56.5 L 76.9,53.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-9 atom-12' d='M 64.9,56.4 L 70.0,53.5' style='fill:none;fill-rule:evenodd;stroke:#FF60B7;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-9 atom-12' d='M 70.0,53.5 L 75.1,50.5' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='18.7' y='35.9' class='atom-0' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >C</text>
<text x='23.6' y='35.9' class='atom-0' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >a</text>
<text x='27.3' y='33.0' class='atom-0' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >2</text>
<text x='29.6' y='33.0' class='atom-0' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >+</text>
<text x='18.7' y='24.1' class='atom-1' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >C</text>
<text x='23.6' y='24.1' class='atom-1' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >a</text>
<text x='27.3' y='21.2' class='atom-1' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >2</text>
<text x='29.6' y='21.2' class='atom-1' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >+</text>
<text x='18.7' y='12.3' class='atom-2' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >C</text>
<text x='23.6' y='12.3' class='atom-2' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >a</text>
<text x='27.3' y='9.5' class='atom-2' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >2</text>
<text x='29.6' y='9.5' class='atom-2' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >+</text>
<text x='3.4' y='71.8' class='atom-3' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='8.2' y='69.0' class='atom-3' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='18.7' y='63.0' class='atom-4' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#FF60B7' >P</text>
<text x='9.8' y='47.6' class='atom-5' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='14.7' y='44.8' class='atom-5' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='27.5' y='78.3' class='atom-6' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='32.4' y='75.4' class='atom-6' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='34.0' y='54.1' class='atom-7' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='45.8' y='71.8' class='atom-8' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='50.7' y='69.0' class='atom-8' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='61.1' y='63.0' class='atom-9' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#FF60B7' >P</text>
<text x='52.2' y='47.6' class='atom-10' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='57.1' y='44.8' class='atom-10' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='69.9' y='78.3' class='atom-11' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='74.8' y='75.4' class='atom-11' style='font-size:4px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='76.4' y='54.1' class='atom-12' style='font-size:7px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
</svg>
 [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O 0 title abstract description 69
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Dorozhkin | Nanodimensional and nanocrystalline calcium orthophosphates | |
Dorozhkin | Nanosized and nanocrystalline calcium orthophosphates | |
Singh et al. | Customized hydroxyapatites for bone-tissue engineering and drug delivery applications: A review | |
Dorozhkin | Nanodimensional and nanocrystalline apatites and other calcium orthophosphates in biomedical engineering, biology and medicine | |
Basirun et al. | Overview of hydroxyapatite–graphene nanoplatelets composite as bone graft substitute: mechanical behavior and in-vitro biofunctionality | |
Mondal et al. | Recent progress on fabrication and drug delivery applications of nanostructured hydroxyapatite | |
Amudha et al. | Enhanced mechanical and biocompatible properties of strontium ions doped mesoporous bioactive glass | |
Zhou et al. | Nanoscale hydroxyapatite particles for bone tissue engineering | |
Mondal et al. | Nano-hydroxyapatite bioactive glass composite scaffold with enhanced mechanical and biological performance for tissue engineering application | |
Cai et al. | Calcium phosphate nanoparticles in biomineralization and biomaterials | |
Uskoković et al. | Nanosized hydroxyapatite and other calcium phosphates: chemistry of formation and application as drug and gene delivery agents | |
Dorozhkin | Nanometric calcium orthophosphates (CaPO4): Preparation, properties and biomedical applications | |
Tiwari et al. | Biomedical materials and diagnostic devices | |
Sikder et al. | Microwave processing of calcium phosphate and magnesium phosphate based orthopedic bioceramics: A state-of-the-art review | |
Kumar et al. | Enhanced mechanical properties and hydrophilic behavior of magnesium oxide added hydroxyapatite nanocomposite: A bone substitute material for load bearing applications | |
Irfan et al. | Overview of hydroxyapatite; composition, structure, synthesis methods and its biomedical uses | |
Zhu et al. | Deformable biomaterials based on ultralong hydroxyapatite nanowires | |
He et al. | Formation of bone-like nanocrystalline apatite using self-assembled liquid crystals | |
Chen et al. | Synthesis of fiber-like monetite without organic additives and its transformation to hydroxyapatite | |
Dos Santos et al. | Manufacturing and characterization of plates for fracture fixation of bone with biocomposites of poly (lactic acid-co-glycolic acid)(PLGA) with calcium phosphates bioceramics | |
Kesse et al. | Unravelling the impact of calcium content on the bioactivity of sol–gel-derived bioactive glass nanoparticles | |
Lu et al. | One-dimensional hydroxyapatite materials: preparation and applications | |
Prasad et al. | Surfactant-assisted synthesis of hydroxyapatite particles: A comprehensive review | |
Feng et al. | Hydrothermal synthesis of hydroxyapatite nanorods and their use in PCL bone scaffold | |
Asadollahzadeh et al. | In vitro apatite formation of calcium phosphate composite synthesized from fish bone |