[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Alhabbab et al., 2015 - Google Patents

Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model

Alhabbab et al., 2015

View HTML @Full View
Document ID
18207463858946832696
Author
Alhabbab R
Blair P
Elgueta R
Stolarczyk E
Marks E
Becker P
Ratnasothy K
Smyth L
Safinia N
Sharif-Paghaleh E
O’Connell S
Noelle R
Lord G
Howard J
Spencer J
Lechler R
Lombardi G
Publication year
Publication venue
Scientific reports

External Links

Snippet

B cells have been reported to promote graft rejection through alloantibody production. However, there is growing evidence that B cells can contribute to the maintenance of tolerance. Here, we used a mouse model of MHC-class I mismatched skin transplantation to …
Continue reading at www.nature.com (HTML) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/569—Immunoassay; Biospecific binding assay for micro-organisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Similar Documents

Publication Publication Date Title
Alhabbab et al. Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model
Martinez-Lopez et al. Microbiota sensing by Mincle-Syk axis in dendritic cells regulates interleukin-17 and-22 production and promotes intestinal barrier integrity
Toubal et al. Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity
Mao et al. Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism
Calcinotto et al. Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression
Diehl et al. Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX3CR1hi cells
Zhuang et al. Graft-infiltrating host dendritic cells play a key role in organ transplant rejection
Nova-Lamperti et al. IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+ T-cell responses
Shin et al. Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+ CD25+ Foxp3+ regulatory T cells
Diana et al. Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes
Berer et al. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
Karim et al. Alloantigen-induced CD25+ CD4+ regulatory T cells can develop in vivo from CD25− CD4+ precursors in a thymus-independent process
Hu et al. Maternal antibiotic treatment protects offspring from diabetes development in nonobese diabetic mice by generation of tolerogenic APCs
Phan et al. Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation
Mosconi et al. Intestinal bacteria induce TSLP to promote mutualistic T-cell responses
Bieber et al. T cells mediate autoantibody-induced cutaneous inflammation and blistering in epidermolysis bullosa acquisita
Fu et al. Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation
Nakanishi et al. Regulatory T cells with superior immunosuppressive capacity emigrate from the inflamed colon to draining lymph nodes
Biswas et al. Negative regulation of Toll‐like receptor signaling plays an essential role in homeostasis of the intestine
Kuo et al. Interleukin-35 enhances Lyme arthritis in Borrelia-vaccinated and-infected mice
Kurkó et al. Suppression of proteoglycan-induced autoimmune arthritis by myeloid-derived suppressor cells generated in vitro from murine bone marrow
Liu et al. Dysfunction of CD19+ CD24hiCD27+ B regulatory cells in patients with bullous pemphigoid
Koyama et al. Promoting regulation via the inhibition of DNAM-1 after transplantation
Mencarelli et al. Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis
Alhabbab et al. Galectin-1 is required for the regulatory function of B cells