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Ramfrez-Solis et al., 1993 - Google Patents

Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments

Ramfrez-Solis et al., 1993

Document ID
18257128376049337640
Author
Ramfrez-Solis R
Zheng H
Whiting J
Krumlauf R
Bradley A
Publication year
Publication venue
Cell

External Links

Snippet

Summary Two Hoxb4 (Hox-2.6) mutations were introduced into the mouse germline. The overt phenotype caused by one of the mutations was assayed on two dlfferent genetic backgrounds, an inbred 129SvEv and a hybrid 129SvEv-C57BL19J. The allele hoxb. 4'is a …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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