[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Atherton et al., 1981 - Google Patents

Peptide synthesis. Part 2. Procedures for solid-phase synthesis using N α-fluorenylmethoxycarbonylamino-acids on polyamide supports. Synthesis of substance P and …

Atherton et al., 1981

Document ID
18118842577911102279
Author
Atherton E
Logan C
Sheppard R
Publication year
Publication venue
Journal of the Chemical Society, Perkin Transactions 1

External Links

Snippet

Use of base-labile Nα-9-fluorenylmethoxycarbonylamino-acids in combination with acid- labile t-butyl or p-alkoxybenzyl side-chain or carboxy-terminal (resin-linkage) protecting groups enables solid-phase peptide synthesis to be carried out under exceptionally mild …
Continue reading at pubs.rsc.org (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution

Similar Documents

Publication Publication Date Title
Atherton et al. Peptide synthesis. Part 2. Procedures for solid-phase synthesis using N α-fluorenylmethoxycarbonylamino-acids on polyamide supports. Synthesis of substance P and of acyl carrier protein 65–74 decapeptide
Sasaki et al. Solid phase synthesis of peptides containing the CH2NH peptide bond isostere
Atherton et al. Peptide synthesis. Part 7. Solid-phase synthesis of conotoxin G1
Bodanszky et al. Synthesis of the vasoactive intestinal peptide (VIP)
Nakagawa et al. Synthesis of protected peptide segments and their assembly on a polymer-bound oxime: application to the synthesis of a peptide model for plasma apolipoprotein AI
US5602231A (en) Process for making peptides
Najjar et al. Solid Phase Peptide Synthesis. VI. The Use of the o-Nitrophenylsulfenyl Group in the Synthesis of the Octadecapeptide Bradykininylbradykinin
US5288464A (en) Solid-phase synthesizer
US5880259A (en) Peptide useful as a ligand
EP0518656B1 (en) Solid phase peptide synthesis
Hermann et al. Amino acid sequence of two cyanogen bromide fragments of glycogen phosphorylase
Atherton et al. Peptide synthesis. Part 6. Protection of the sulphydryl group of cysteine in solid-phase synthesis using N α-fluorenylmethoxycarbonylamino acids. Linear oxytocin derivatives
Yamashiro et al. Human pituitary growth hormone. 36. Solid phase synthesis of the carboxyl terminal cyclic dodecapeptide
ATHERTON et al. Synthesis of a 21-residue fragment of human proinsulin by the polyamide solid phase method
Lloyd-Williams et al. Convergent solid-phase peptide synthesis. X. Synthesis and purification of protected peptide fragments using the photolabile Nbb-resin
Kitada et al. Synthesis of rhodotorucine A, the inducing factor of mating tube formation of Rhodosporidium toruloides
Atherton et al. Peptide synthesis. Part 3. Comparative solid-phase syntheses of human β-endorphin on polyamide supports using t-butoxycarbonyl and fluorenylmethoxycarbonyl protecting groups
Kasper et al. Subtilisin BPN': III. ISOLATION AND SEQUENCE OF 10 PEPTIDES FROM THE TRYPTIC DIGEST
Sheppared et al. A new protecting group combination for solid phase synthesis of protected peptides
Mihara et al. Synthesis of the 60 amino acid homeo domain and smaller fragments of the Drosophila gene regulatory protein Antennapedia by a segment synthesis-condensation approach
Hase et al. SYMMETRICAL DISULFIDE BONDS AS S‐PROTECTING GROUPS AND THEIR CLEAVAGE BY DITHIOTHREITOL: SYNTHESIS OF OXYTOCIN WITH HIGH BIOLOGICAL ACTIVITY
KHAN et al. SYNTHESIS OF THE DODECAPEPTIDE‐α MATING FACTOR OF SACCHAROMYCES CEREVISIAE
KALJUSTE et al. A new general solid‐phase method for the synthesis of backbone‐to‐backbone cyclized peptides
Or et al. Cysteine alkylation in unprotected peptides: synthesis of a carbavasopressin analog by intramolecular cysteine alkylation
Akaji et al. Fmoc-based solid-phase peptide synthesis using a new t-alcohol type 4-(1′, 1′-dimethyl-1′-hydroxypropyl) phenoxyacetyl handle (DHPP)–resin (Fmoc= fluoren-9-ylmethoxycarbonyl)