Lin, 2024 - Google Patents
Cell Type-Specific FGF13 Regulation of Neuronal FunctionLin, 2024
- Document ID
- 17955720294031417521
- Author
- Lin S
- Publication year
External Links
Snippet
Abstract Developmental and Epileptic Encephalopathies (DEEs) are a class of devastating neurological disorders characterized by recurrent seizures, developmental delay, and cognitive impairment. DEEs are exacerbated by disruptions to excitatory/inhibitory balance …
- 102000003684 fibroblast growth factor 13 0 title abstract description 410
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/027—New breeds of vertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Jego et al. | Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus | |
AU2017279749B2 (en) | Optogenetic control of reward-related behaviors | |
Sun et al. | Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia | |
Geoffroy et al. | Effects of PTEN and Nogo codeletion on corticospinal axon sprouting and regeneration in mice | |
Uchida et al. | Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing | |
Terzic et al. | Temporal manipulation of Cdkl5 reveals essential postdevelopmental functions and reversible CDKL5 deficiency disorder–related deficits | |
KR102364249B1 (en) | Anti-RYK antibodies and methods of use thereof | |
Liu et al. | Acid-sensing ion channel 1a contributes to hippocampal LTP inducibility through multiple mechanisms | |
Yu et al. | CaMKII controls whether touch is painful | |
Hua et al. | Partial interchangeability of Fz3 and Fz6 in tissue polarity signaling for epithelial orientation and axon growth and guidance | |
Kharouf et al. | The hyperpolarization‐activated cyclic nucleotide‐gated 4 channel as a potential anti‐seizure drug target | |
Kolling et al. | Modulating the excitability of olfactory output neurons affects whole-body metabolism | |
Ogino et al. | Defects of the glycinergic synapse in zebrafish | |
Lin | Cell Type-Specific FGF13 Regulation of Neuronal Function | |
Lin et al. | Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism | |
Bandarabadi et al. | Orexin action on the dopaminergic system modulates theta during REM sleep and wakefulness | |
Flanigan | Orexin inputs to GABAergic lateral habenula neurons control aggression valence | |
Meza Santoscoy | Analysis of the transcriptional and behavioural responses to seizure onset in a zebrafish model of epilepsy. | |
Martin Batista | The anticonvulsant and neuroprotective roles of sgk1. 1 | |
Chidiac | Development and characterization of pain-related sodium channel mouse model for Scn10aG1663S | |
Astrocyte-Mediated | ASNTR 2023 Abstracts | |
Browe | Cannabinoid Modulation of Development and Neuroprotection in African Naked Mole-Rats | |
Terzic | Temporal and Molecular Insights into the Pathophysiology of CDKL5 Deficiency Disorder | |
Marocha | The Clustered Protocadherins in the Form and Function of Cerebellar Purkinje Cells | |
Landy | Sensory Neurogenesis and the Role of PRDM12 in Nociceptor Development and Function |