Trojanowska, 2008 - Google Patents
Role of PDGF in fibrotic diseases and systemic sclerosisTrojanowska, 2008
View HTML- Document ID
- 17745463219103775753
- Author
- Trojanowska M
- Publication year
- Publication venue
- Rheumatology
External Links
Snippet
PDGF functions as a primary mitogen and chemoattractant for cells of mesenchymal origin. Members of the PDGF family play an important role during embryonic development and contribute to the maintenance of connective tissue in adults. Deregulation of PDGF …
- 108010038512 Platelet-Derived Growth Factor 0 title abstract description 62
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Trojanowska | Role of PDGF in fibrotic diseases and systemic sclerosis | |
Mousa et al. | Proangiogenesis action of the thyroid hormone analog 3, 5-diiodothyropropionic acid (DITPA) is initiated at the cell surface and is integrin mediated | |
Thamotharan et al. | Hormonal regulation of oligopeptide transporter pept-1 in a human intestinal cell line | |
Carlson et al. | Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice | |
Dow et al. | Fibroblast growth factor 2: its structure and property, paracrine function, tumor angiogenesis, and prostate-related mitogenic and oncogenic functions | |
Ota et al. | Elevation of fatty acid-binding protein 4 is predisposed by family history of hypertension and contributes to blood pressure elevation | |
Laurén et al. | Is angiopoietin-2 necessary for the initiation of tumor angiogenesis? | |
Zhang et al. | A dual role of lipasin (betatrophin) in lipid metabolism and glucose homeostasis: consensus and controversy | |
Sierra-Honigmann et al. | Biological action of leptin as an angiogenic factor | |
Chen et al. | PECAM-1 is necessary for flow-induced vascular remodeling | |
Wells | V. TGF-β signaling pathways | |
Ricupero et al. | Regulation of connective tissue growth factor expression by prostaglandin E2 | |
Short et al. | Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts | |
Chang et al. | Pericytes modulate endothelial sprouting | |
Smith et al. | Biology of the renal pericyte | |
Stevens et al. | Modulation of receptor tyrosine kinase activity through alternative splicing of ligands and receptors in the VEGF-A/VEGFR axis | |
Karkkainen et al. | Molecular regulation of lymphangiogenesis and targets for tissue oedema | |
He et al. | Loureirin B inhibits hypertrophic scar formation via inhibition of the TGF-β1-ERK/JNK pathway | |
Okazaki et al. | The novel inhibitor PRI-724 for Wnt/β-catenin/CBP signaling ameliorates bleomycin-induced pulmonary fibrosis in mice | |
Stannard et al. | Vascular endothelial growth factor synergistically enhances induction of E-selectin by tumor necrosis factor-α | |
Muradashvili et al. | Fibrinogen-induced increased pial venular permeability in mice | |
Pietrangelo | Molecular insights into the pathogenesis of hereditary haemochromatosis | |
Asashima et al. | Serum levels of BAFF are increased in bullous pemphigoid but not in pemphigus vulgaris | |
Ström et al. | Fibulin-2 is present in murine vascular lesions and is important for smooth muscle cell migration | |
Mezzano et al. | Gremlin and renal diseases: ready to jump the fence to clinical utility? |