[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Gajda et al., 2020 - Google Patents

Combinatory treatment with miR-7-5p and drug-loaded cubosomes effectively impairs cancer cells

Gajda et al., 2020

View HTML
Document ID
17550282571626725128
Author
Gajda E
Godlewska M
Mariak Z
Nazaruk E
Gawel D
Publication year
Publication venue
International journal of molecular sciences

External Links

Snippet

Background: Multidrug resistance (MDR) is an emerging problem in the treatment of cancer. Therefore, there is a necessity for novel strategies that would sensitize tumor cells to the administered chemotherapeutics. One of the innovative approaches in fighting drug …
Continue reading at www.mdpi.com (HTML) (other versions)

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Similar Documents

Publication Publication Date Title
Gajda et al. Combinatory treatment with miR-7-5p and drug-loaded cubosomes effectively impairs cancer cells
Ramos et al. Battling chemoresistance in cancer: root causes and strategies to uproot them
Hattinger et al. Drug resistance in osteosarcoma: emerging biomarkers, therapeutic targets and treatment strategies
Rugamba et al. Silibinin regulates tumor progression and tumorsphere formation by suppressing PD-L1 expression in non-small cell lung cancer (NSCLC) cells
Pollutri et al. TP53/MicroRNA interplay in hepatocellular carcinoma
C. de SL Oliveira et al. Effect of oxaliplatin-loaded poly (d, l-Lactide-co-Glycolic Acid)(PLGA) nanoparticles combined with retinoic acid and cholesterol on apoptosis, drug resistance, and metastasis factors of colorectal cancer
Eid et al. Targeting cancer stem cells as the key driver of carcinogenesis and therapeutic resistance
Ambrosio et al. Carbosilane dendrimers loaded with siRNA targeting Nrf2 as a tool to overcome cisplatin chemoresistance in bladder cancer cells
Zhang et al. The miRNA-21-5p payload in exosomes from M2 macrophages drives tumor cell aggression via PTEN/Akt signaling in renal cell carcinoma
Bahar et al. Establishment of acquired cisplatin resistance in ovarian cancer cell lines characterized by enriched metastatic properties with increased twist expression
Doan et al. Glioblastoma multiforme stem cell cycle arrest by alkylaminophenol through the modulation of EGFR and CSC signaling pathways
Scherr et al. Knockdown of Atg7 induces nuclear-LC3 dependent apoptosis and augments chemotherapy in colorectal cancer cells
Zhang et al. Carbon dioxide-derived biodegradable and cationic polycarbonates as a new siRNA carrier for gene therapy in pancreatic cancer
Gajda et al. The role of miRNA-7 in the biology of cancer and modulation of drug resistance
Yang et al. Inhibition of miR-214-3p aids in preventing epithelial ovarian cancer malignancy by increasing the expression of LHX6
Pengnam et al. Synergistic effect of doxorubicin and sirna-mediated silencing of mcl-1 using cationic niosomes against 3d mcf-7 spheroids
Kim et al. MiR-1208 increases the sensitivity to cisplatin by targeting TBCK in renal cancer cells
Ke et al. Cyclodextrin-based hybrid polymeric complex to overcome dual drug resistance mechanisms for cancer therapy
Kang et al. Metformin and niclosamide synergistically suppress Wnt and YAP in APC-mutated colorectal cancer
Panvongsa et al. More than a bubble: Extracellular vesicle microRNAs in head and neck squamous cell carcinoma
Kucheryavykh et al. Targeted delivery of nanoparticulate cytochrome C into glioma cells through the proton-coupled folate transporter
Kon et al. Resveratrol enhances mRNA and siRNA lipid nanoparticles primary CLL cell transfection
Liu et al. Targeted co-delivery of gefitinib and rapamycin by aptamer-modified nanoparticles overcomes EGFR-TKI resistance in NSCLC via promoting autophagy
Gote et al. Octreotide-Targeted Lcn2 siRNA PEGylated liposomes as a treatment for metastatic breast cancer
Cai et al. LncRNA SNHG1 facilitates Tumor Proliferation and represses apoptosis by regulating PPARγ ubiquitination in bladder Cancer