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Kusakabe et al., 1979 - Google Patents

Occurrence of a novel enzyme, L-lysine oxidase with antitumor activity in culture extract of Trichoderma viride

Kusakabe et al., 1979

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Document ID
17300898876633318611
Author
Kusakabe H
Kodama K
Machida H
Midorikawa Y
Kuninaka A
Misono H
soda K
Publication year
Publication venue
Agricultural and Biological Chemistry

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An aqueous extract of culture of Trichoderma viride Y244–2 on wheat bran showed antitumor activity against L5178Y mouse leukemic cells in vitro and L1210 mouse leukemia in vivo. The principle of the antitumor activity was proved to be an l-lysine-oxidizing enzyme …
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
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