Lienne et al., 1988 - Google Patents
Optimization of the direct chiral separation of potential cytotoxic α-methylene-γ-butyrolactones and α-methylene-γ-butyrolactams by liquid chromatographyLienne et al., 1988
- Document ID
- 17254993914079029889
- Author
- Lienne M
- Caude M
- Rosset R
- Tambute A
- Publication year
- Publication venue
- Journal of Chromatography A
External Links
Snippet
The direct enantiomeric resolution of a series of racemic α-methylene-γ-butyrolactones and α-methylene-γ-butyrolactams was carried out on various commercially available chiral stationary phases (CSPs). Particular interest was paid to compounds which exhibit …
- 230000001472 cytotoxic 0 title abstract description 11
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3257—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such
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