Jakumeit-Morgott et al., 1975 - Google Patents
On the activity of brain phospholipase A2 towards specifically labelled glycerophospholipids during subacute sclerosing panencephalitisJakumeit-Morgott et al., 1975
- Document ID
- 1715577198552750188
- Author
- Jakumeit-Morgott U
- Woelk H
- Kanig K
- Publication year
- Publication venue
- Archiv für Psychiatrie und Nervenkrankheiten
External Links
Snippet
Diacyl-sn-glycero-3-phosphorylcholine,-ethanolamine and-serine, specifically labelled with different fatty acids at either the 1-or 2-position, were prepared enzymatically using the acyltransferase system of rat liver microsomes. The substrates were subjected to hydrolysis …
- 230000000694 effects 0 title abstract description 28
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P-C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P-C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P-C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Brites et al. | Functions and biosynthesis of plasmalogens in health and disease | |
Wells et al. | Neural membrane phospholipids in Alzheimer disease | |
Cooper et al. | The differentiation of phospholipase A1 and A2 in rat and human nervous tissues | |
Gattaz et al. | Increased platelet phospholipase A2 activity in schizophrenia | |
Farooqui et al. | Neurochemical aspects of Alzheimer's disease: involvement of membrane phospholipids | |
Pettegrew et al. | Brain membrane phospholipid alterations in Alzheimer's disease | |
Hatch | Cardiolipin: biosynthesis, remodeling and trafficking in the heart and mammalian cells | |
Gattaz et al. | Decreased phospholipase A2 activity in Alzheimer brains | |
Mahadik et al. | Plasma membrane phospholipid and cholesterol distribution of skin fibroblasts from drug-naive patients at the onset of psychosis | |
Heymans et al. | Deficiency of plasmalogens in the cerebro-hepato-renal (Zellweger) syndrome | |
Glynn | Neuropathy target esterase and phospholipid deacylation | |
Farooqui et al. | Stimulation of lipolytic enzymes in Alzheimer’s disease | |
Ross et al. | Characterization of a novel phospholipase A2 activity in human brain | |
Göpfert et al. | 2′, 3′‐Cyclic nucleotide 3′‐phosphohydrolase and lipids of myelin from multiple sclerosis and normal brains | |
Smith et al. | Model systems for study of perturbations of myelin metabolism | |
Pandya et al. | Effect of long-term aluminum feeding on lipid/phospholipid profiles of rat brain myelin | |
Kumara-Siri et al. | Enzymes of phospholipid synthesis: axonal versus Schwann cell distribution | |
Watson et al. | 1, 2-Diacylglycerols do not potentiate the action of phospholipases A2 and C in human platelets | |
Shukla et al. | Ethanol and lipid metabolic signaling | |
Jakumeit-Morgott et al. | On the activity of brain phospholipase A2 towards specifically labelled glycerophospholipids during subacute sclerosing panencephalitis | |
Johnson et al. | Fatty acid composition of lipids in cerebral myelin and synaptosomes in phenylketonuria and Down syndrome | |
Jones et al. | Stimulation of phospholipase D activity and phosphatidic acid production by norepinephrine in rat aorta | |
Drgová et al. | Changes of phospholipid composition and superoxide dismutase activity during global brain ischemia and reperfusion in rats | |
Neu et al. | Investigations of the lipid metabolism of the white matter in multiple sclerosis Changes in glycero-phosphatides and lipid-splitting enzymes | |
Shimohama et al. | Alteration of myo-inositol monophosphatase in Alzheimer's disease brains |