Masaki et al., 2005 - Google Patents
Smad1 protects cardiomyocytes from ischemia-reperfusion injuryMasaki et al., 2005
View HTML- Document ID
- 16908258673051414353
- Author
- Masaki M
- Izumi M
- Oshima Y
- Nakaoka Y
- Kuroda T
- Kimura R
- Sugiyama S
- Terai K
- Kitakaze M
- Yamauchi-Takihara K
- Kawase I
- Hirota H
- Publication year
- Publication venue
- Circulation
External Links
Snippet
Background—We previously reported that bone morphogenetic protein 2 (BMP2) protected against apoptosis of serum-deprived cardiomyocytes via induction of Bcl-xL through the Smad1 pathway. To investigate whether Smad1 signaling promotes cell survival in the adult …
- 108010077552 Smad1 Protein 0 title abstract description 114
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/574—Immunoassay; Biospecific binding assay for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57496—Immunoassay; Biospecific binding assay for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Masaki et al. | Smad1 protects cardiomyocytes from ischemia-reperfusion injury | |
Huang et al. | Thioredoxin-2 inhibits mitochondrial reactive oxygen species generation and apoptosis stress kinase-1 activity to maintain cardiac function | |
Heinolainen et al. | VEGFR3 modulates vascular permeability by controlling VEGF/VEGFR2 signaling | |
Nishiga et al. | MicroRNA-33 controls adaptive fibrotic response in the remodeling heart by preserving lipid raft cholesterol | |
Yamada et al. | WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic β-cells | |
Donaldson et al. | Estrogen attenuates left ventricular and cardiomyocyte hypertrophy by an estrogen receptor–dependent pathway that increases calcineurin degradation | |
Xu et al. | YTHDF2 alleviates cardiac hypertrophy via regulating Myh7 mRNA decoy | |
Vakhrusheva et al. | Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice | |
Luo et al. | SIRT4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity | |
Ding et al. | Cardiac peroxisome proliferator-activated receptor δ is essential in protecting cardiomyocytes from oxidative damage | |
Perrotta et al. | Partial inhibition of glycolysis reduces atherogenesis independent of intraplaque neovascularization in mice | |
Hsu et al. | Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes | |
Wang et al. | Targeted disruption of Smad4 in cardiomyocytes results in cardiac hypertrophy and heart failure | |
White et al. | Activity of the estrogen-metabolizing enzyme cytochrome P450 1B1 influences the development of pulmonary arterial hypertension | |
Maekawa et al. | Inhibiting p90 ribosomal S6 kinase prevents Na+-H+ exchanger–mediated cardiac ischemia-reperfusion injury | |
Hilfiker-Kleiner et al. | Continuous glycoprotein-130–mediated signal transducer and activator of transcription-3 activation promotes inflammation, left ventricular rupture, and adverse outcome in subacute myocardial infarction | |
Mercer et al. | DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome | |
Liu et al. | DUSP8 regulates cardiac ventricular remodeling by altering ERK1/2 signaling | |
Fan et al. | Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity | |
Ikeuchi et al. | Overexpression of mitochondrial transcription factor a ameliorates mitochondrial deficiencies and cardiac failure after myocardial infarction | |
Takeda et al. | Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system | |
Bushdid et al. | NFATc3 and NFATc4 are required for cardiac development and mitochondrial function | |
Widyantoro et al. | Endothelial cell–derived endothelin-1 promotes cardiac fibrosis in diabetic hearts through stimulation of endothelial-to-mesenchymal transition | |
Hilfiker-Kleiner et al. | Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury | |
Luk et al. | FAK signalling controls insulin sensitivity through regulation of adipocyte survival |