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Svetlanov et al., 2012 - Google Patents

Francisella tularensis tmRNA system mutants are vulnerable to stress, avirulent in mice, and provide effective immune protection

Svetlanov et al., 2012

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Document ID
16843874128837644831
Author
Svetlanov A
Puri N
Mena P
Koller A
Karzai A
Publication year
Publication venue
Molecular microbiology

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Snippet

Through targeted inactivation of the ssrA and smpB genes, we establish that the trans‐ translation process is necessary for normal growth, adaptation to cellular stress and virulence by the bacterial pathogen Francisella tularensis. The mutant bacteria grow slower …
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