Papatriantafyllou et al., 2012 - Google Patents
Dickkopf-3, an immune modulator in peripheral CD8 T-cell tolerancePapatriantafyllou et al., 2012
View PDF- Document ID
- 1668600033646414946
- Author
- Papatriantafyllou M
- Moldenhauer G
- Ludwig J
- Tafuri A
- Garbi N
- Hollmann G
- Küblbeck G
- Klevenz A
- Schmitt S
- Pougialis G
- Niehrs C
- Gröne H
- Hämmerling G
- Arnold B
- Oelert T
- Publication year
- Publication venue
- Proceedings of the National Academy of Sciences
External Links
Snippet
In healthy individuals, T cells react against incoming pathogens, but remain tolerant to self- antigens, thereby preventing autoimmune reactions. CD4 regulatory T cells are major contributors in induction and maintenance of peripheral tolerance, but a regulatory role has …
- 210000001744 T-Lymphocytes 0 title abstract description 200
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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