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Haviv, 2009 - Google Patents

A simplified in vitro ligation approach to clone an E1B55k-deleted double-targeted conditionally-replicative adenovirus

Haviv, 2009

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Document ID
16476689801315142444
Author
Haviv Y
Publication year
Publication venue
Virology Journal

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Background Construction of conditionally-replicative Adenovirus (CRAd) is complex and time-consuming. While homologous recombination (HR) using a two-plasmid system in bacteria is commonly used to generate CRAds, alternative methods may be required when …
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