Udenfriend et al., 1985 - Google Patents
Scintillation proximity radioimmunoassay utilizing 125I-labeled ligands.Udenfriend et al., 1985
View PDF- Document ID
- 16327260890495942354
- Author
- Udenfriend S
- Gerber L
- Brink L
- Spector S
- Publication year
- Publication venue
- Proceedings of the National Academy of Sciences
External Links
Snippet
A unique type of radioimmunoassay is described that does not require centrifugation or separation. Microbeads containing a fluorophor are covalently linked to antibody. When an 125I-labeled antigen is added it binds to the beads and, by its proximity, the emitted short …
- 230000027455 binding 0 title abstract description 49
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/543—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
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- G01N33/531—Production of immunochemical test materials
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
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