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He et al., 2011 - Google Patents

Does positive selection drive transcription factor binding site turnover? A test with Drosophila cis-regulatory modules

He et al., 2011

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Document ID
16292099908454679915
Author
He B
Holloway A
Maerkl S
Kreitman M
Publication year
Publication venue
PLoS genetics

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Transcription factor binding site (s)(TFBS) gain and loss (ie, turnover) is a well-documented feature of cis-regulatory module (CRM) evolution, yet little attention has been paid to the evolutionary force (s) driving this turnover process. The predominant view, motivated by its …
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    • G06F19/22Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or SNP [Single-Nucleotide Polymorphism] discovery or sequence alignment
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    • G06F19/18Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for functional genomics or proteomics, e.g. genotype-phenotype associations, linkage disequilibrium, population genetics, binding site identification, mutagenesis, genotyping or genome annotation, protein-protein interactions or protein-nucleic acid interactions
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