Sierig et al., 2003 - Google Patents
Cytotoxic effects of streptolysin O and streptolysin S enhance the virulence of poorly encapsulated group A streptococciSierig et al., 2003
View PDF- Document ID
- 15964166236717701181
- Author
- Sierig G
- Cywes C
- Wessels M
- Ashbaugh C
- Publication year
- Publication venue
- Infection and immunity
External Links
Snippet
Although the toxicity of streptolysin O (SLO) and streptolysin S (SLS) in purified group A streptococci (GAS) has been established, the effect of these molecules in natural infection is not well understood. To identify whether biologically relevant concentrations of SLO and …
- 241001505901 Streptococcus sp. 'group A' 0 title abstract description 202
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Micro-organisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Sierig et al. | Cytotoxic effects of streptolysin O and streptolysin S enhance the virulence of poorly encapsulated group A streptococci | |
| Heath et al. | A two-component regulatory system, CsrR-CsrS, represses expression of three Streptococcus pyogenes virulence factors, hyaluronic acid capsule, streptolysin S, and pyrogenic exotoxin B | |
| Hyams et al. | Streptococcus pneumoniae resistance to complement-mediated immunity is dependent on the capsular serotype | |
| Limbago et al. | Role of streptolysin O in a mouse model of invasive group A streptococcal disease | |
| Charland et al. | Streptococcus suis serotype 2 interactions with human brain microvascular endothelial cells | |
| Sinha et al. | Heterologously expressed Staphylococcus aureus fibronectin-binding proteins are sufficient for invasion of host cells | |
| Simoons-Smit et al. | The role of K antigens as virulence factors in Klebsiella | |
| Rivera Starr et al. | Role of hyaluronidase in subcutaneous spread and growth of group A streptococcus | |
| Watts et al. | Staphylococcus aureus strains that express serotype 5 or serotype 8 capsular polysaccharides differ in virulence | |
| Nakano et al. | Demonstration of Streptococcus mutans with a cell wall polysaccharide specific to a new serotype, k, in the human oral cavity | |
| Wright et al. | Identification of a group 1-like capsular polysaccharide operon for Vibrio vulnificus | |
| Medina et al. | Intracellular survival of Streptococcus pyogenes in polymorphonuclear cells results in increased bacterial virulence | |
| Salcedo et al. | Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo | |
| Lukomski et al. | Genetic inactivation of an extracellular cysteine protease (SpeB) expressed by Streptococcus pyogenes decreases resistance to phagocytosis and dissemination to organs | |
| Jansen et al. | Hydrogen peroxide-mediated killing of Caenorhabditis elegans by Streptococcus pyogenes | |
| Reckseidler-Zenteno et al. | The capsular polysaccharide of Burkholderia pseudomallei contributes to survival in serum by reducing complement factor C3b deposition | |
| Staali et al. | Streptococcus pyogenes expressing M and M‐like surface proteins are phagocytosed but survive inside human neutrophils | |
| Cheng et al. | Antibody against surface-bound C5a peptidase is opsonic and initiates macrophage killing of group B streptococci | |
| Shankar-Sinha et al. | The Klebsiella pneumoniae O antigen contributes to bacteremia and lethality during murine pneumonia | |
| Xu et al. | Role of a cytotoxic enterotoxin in Aeromonas-mediated infections: development of transposon and isogenic mutants | |
| Tuchscherr et al. | Capsule-negative Staphylococcus aureus induces chronic experimental mastitis in mice | |
| Flores et al. | Asymptomatic carriage of group A Streptococcus is associated with elimination of capsule production | |
| Wessels | Capsular polysaccharide of group A Streptococcus | |
| Sydenham et al. | Salmonella enterica serovar Typhimurium surA mutants are attenuated and effective live oral vaccines | |
| Ashbaugh et al. | Absence of a cysteine protease effect on bacterial virulence in two murine models of human invasive group A streptococcal infection |