Klauss et al., 2018 - Google Patents
Genetically induced vs. classical animal models of chronic pancreatitis: a critical comparisonKlauss et al., 2018
View PDF- Document ID
- 15800978184146379674
- Author
- Klauss S
- Schorn S
- Teller S
- Steenfadt H
- Friess H
- Ceyhan G
- Demir I
- Publication year
- Publication venue
- The FASEB Journal
External Links
Snippet
Chronic pancreatitis (CP) is an utmost complex disease that is pathogenetically linked to pancreas‐intrinsic (eg, duct obstruction), environmental‐toxic (eg, alcohol, smoking), and genetic factors. Studying such a complex disease naturally requires validated experimental …
- 208000000668 Chronic Pancreatitis 0 title abstract description 220
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Klauss et al. | Genetically induced vs. classical animal models of chronic pancreatitis: a critical comparison | |
| Yeo et al. | Intensified mitophagy in skeletal muscle with aging is downregulated by PGC-1alpha overexpression in vivo | |
| Chan et al. | Acute pancreatitis: animal models and recent advances in basic research | |
| Nilius et al. | Transient receptor potential cation channels in disease | |
| Sinha et al. | Dietary methionine restriction inhibits prostatic intraepithelial neoplasia in TRAMP mice | |
| ES2738101T3 (en) | Mouse model of steatohepatitis-liver cancer | |
| Liu et al. | Spinal microglia initiate and maintain hyperalgesia in a rat model of chronic pancreatitis | |
| JP2019069942A (en) | Peptide therapeutics and methods for using the same | |
| Zhao et al. | Cardiac-specific overexpression of insulin-like growth factor I (IGF-1) rescues lipopolysaccharide-induced cardiac dysfunction and activation of stress signaling in murine cardiomyocytes | |
| TW201729833A (en) | Methods and compositions for the treatment of amyloidosis | |
| US20090131302A1 (en) | Transient receptor potential vanilloid 1 and uses thereof | |
| Oruc et al. | Theories, mechanisms, and models of alcoholic chronic pancreatitis | |
| Fawzy et al. | Mito-TEMPO improved L-Arginine-induced acute pancreatitis in rats via TLR-4/NF-кB/NLRP3 inflammasome downregulation and antioxidant properties | |
| Thillaye-Goldenberg et al. | Delayed onset and decreased severity of experimental autoimmune uveoretinitis in mice lacking nitric oxide synthase type 2 | |
| KR20220038328A (en) | Composition for preventing or treating neuroinflammation diseases comprising bee venom extract | |
| Venanzi et al. | Context-dependent effects of the ketogenic diet on retinal ganglion cell survival and axonal regeneration after optic nerve injury | |
| EP4424317A1 (en) | Medicine for preventing or treating enteritis and intestinal cancer | |
| Kalyn | Neurotoxic and Genetic Impacts on Dopaminergic Neuron Death and Regeneration in Zebrafish (Danio rerio) | |
| CA3053059C (en) | Compounds for use in the prevention and/or treatment of non-alcoholic fat liver disease and non-alcoholic steatohepatitis | |
| WO2017214383A1 (en) | USE OF C1q/TNF-RELATED PROTEIN-1 (CTRP1) TO TREAT FATTY LIVER DISEASE | |
| da Conceição | A neuroendocrine strategy to delay aging | |
| Liu et al. | Huoxue Tongjiang decoction-resisted reflux esophagitis by activation stem cell factor/c-kit/interstitial cell of cajal pathway and regulating the T-helper 17/regulatory T-cells balance in rats | |
| Nasrallah | Effect of a Naturally Occurring Ghrelin Splice Variant on Substantia Nigra Dopamine Neurons | |
| Pirzgalska | Neuro-Immune Interactions in Obesity | |
| Pereira | Mechanisms of Physiological Regulation During Caloric Overload in Drosophila |