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Venkat et al., 2018 - Google Patents

Multinucleotide mutations cause false inferences of lineage-specific positive selection

Venkat et al., 2018

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Document ID
15797259581928383195
Author
Venkat A
Hahn M
Thornton J
Publication year
Publication venue
Nature ecology & evolution

External Links

Snippet

Phylogenetic tests of adaptive evolution, such as the widely used branch-site test (BST), assume that nucleotide substitutions occur singly and independently. Recent research has shown that errors at adjacent sites often occur during DNA replication, and the resulting …
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    • G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
    • G06F19/22—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or SNP [Single-Nucleotide Polymorphism] discovery or sequence alignment
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
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