Fittipaldi et al., 2008 - Google Patents
D-alanylation of lipoteichoic acid contributes to the virulence of Streptococcus suisFittipaldi et al., 2008
View PDF- Document ID
- 15570956841877396275
- Author
- Fittipaldi N
- Sekizaki T
- Takamatsu D
- Harel J
- Dominguez-Punaro M
- Von Aulock S
- Draing C
- Marois C
- Kobisch M
- Gottschalk M
- Publication year
- Publication venue
- Infection and immunity
External Links
Snippet
We generated by allelic replacement a Δ dltA mutant of a virulent Streptococcus suis serotype 2 field strain and evaluated the contribution of lipoteichoic acid (LTA) d-alanylation to the virulence traits of this swine pathogen and zoonotic agent. The absence of LTA d …
- 241000194021 Streptococcus suis 0 title abstract description 77
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/569—Immunoassay; Biospecific binding assay for micro-organisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56916—Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/569—Immunoassay; Biospecific binding assay for micro-organisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56938—Staphylococcus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Fittipaldi et al. | D-alanylation of lipoteichoic acid contributes to the virulence of Streptococcus suis | |
Phelps et al. | Relative roles of listeriolysin O, InlA, and InlB in Listeria monocytogenes uptake by host cells | |
Ibrahim et al. | Control of virulence by the two-component system CiaR/H is mediated via HtrA, a major virulence factor of Streptococcus pneumoniae | |
Albarracin Orio et al. | Compensatory evolution of pbp mutations restores the fitness cost imposed by β-lactam resistance in Streptococcus pneumoniae | |
Grundmeier et al. | Truncation of fibronectin-binding proteins in Staphylococcus aureus strain Newman leads to deficient adherence and host cell invasion due to loss of the cell wall anchor function | |
Vanier et al. | Invasion of porcine brain microvascular endothelial cells by Streptococcus suis serotype 2 | |
de Greeff et al. | Contribution of fibronectin-binding protein to pathogenesis of Streptococcus suis serotype 2 | |
Takeuchi et al. | The contribution of suilysin to the pathogenesis of Streptococcus suis meningitis | |
Nallapareddy et al. | Endocarditis and biofilm-associated pili of Enterococcus faecalis | |
Fittipaldi et al. | Significant contribution of the pgdA gene to the virulence of Streptococcus suis | |
Innocentin et al. | Lactococcus lactis expressing either Staphylococcus aureus fibronectin-binding protein A or Listeria monocytogenes internalin A can efficiently internalize and deliver DNA in human epithelial cells | |
Brinster et al. | C-terminal WxL domain mediates cell wall binding in Enterococcus faecalis and other gram-positive bacteria | |
Konto-Ghiorghi et al. | Dual role for pilus in adherence to epithelial cells and biofilm formation in Streptococcus agalactiae | |
Sabet et al. | The Listeria monocytogenes virulence factor InlJ is specifically expressed in vivo and behaves as an adhesin | |
Quereda et al. | Listeriolysin S is a streptolysin S-like virulence factor that targets exclusively prokaryotic cells in vivo | |
Atalla et al. | Staphylococcus aureus small colony variants (SCVs) and their role in disease | |
Xu et al. | The two-component system NisK/NisR contributes to the virulence of Streptococcus suis serotype 2 | |
Brinch et al. | Plectasin shows intracellular activity against Staphylococcus aureus in human THP-1 monocytes and in a mouse peritonitis model | |
Auger et al. | Role of the Streptococcus suis serotype 2 capsular polysaccharide in the interactions with dendritic cells is strain-dependent but remains critical for virulence | |
Lecours et al. | Sialylation of Streptococcus suis serotype 2 is essential for capsule expression but is not responsible for the main capsular epitope | |
Chuzeville et al. | Serotype-specific role of antigen I/II in the initial steps of the pathogenesis of the infection caused by Streptococcus suis | |
Mudahi-Orenstein et al. | Cytadherence-deficient mutants of Mycoplasma gallisepticum generated by transposon mutagenesis | |
Auger et al. | The bias of experimental design, including strain background, in the determination of critical Streptococcus suis serotype 2 virulence factors | |
Li et al. | Characterization and functional analysis of PnuC that is involved in the oxidative stress tolerance and virulence of Streptococcus suis serotype 2 | |
Ye et al. | Pneumococcal LytR protein is required for the surface attachment of both capsular polysaccharide and teichoic acids: essential for pneumococcal virulence |