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Filsinger et al., 2021 - Google Patents

Characterizing the portability of phage-encoded homologous recombination proteins

Filsinger et al., 2021

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Document ID
15485093758375400823
Author
Filsinger G
Wannier T
Pedersen F
Lutz I
Zhang J
Stork D
Debnath A
Gozzi K
Kuchwara H
Volf V
Wang S
Rios X
Gregg C
Lajoie M
Shipman S
Aach J
Laub M
Church G
Publication year
Publication venue
Nature chemical biology

External Links

Snippet

Efficient genome editing methods are essential for biotechnology and fundamental research. Homologous recombination (HR) is the most versatile method of genome editing, but techniques that rely on host RecA-mediated pathways are inefficient and laborious. Phage …
Continue reading at www.ncbi.nlm.nih.gov (HTML) (other versions)

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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