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Xiao et al., 2023 - Google Patents

Fighting cancer by triggering non-canonical mitochondrial permeability transition-driven necrosis through reactive oxygen species induction

Xiao et al., 2023

Document ID
15205108198460717188
Author
Xiao Q
Zhong B
Hou Y
Wang M
Guo B
Lin L
Zhou Y
Chen X
Publication year
Publication venue
Free Radical Biology and Medicine

External Links

Snippet

Non-apoptotic necrosis shows therapeutic potential for the treatment of various diseases, especially cancer. Mitochondrial permeability transition (MPT)-driven necrosis is a form of non-apoptotic cell death triggered by oxidative stress and cytosolic Ca 2+ overload, and …
Continue reading at www.sciencedirect.com (other versions)

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    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
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