Wang et al., 2022 - Google Patents
Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-responseWang et al., 2022
View HTML- Document ID
- 14958975407483326902
- Author
- Wang D
- Wu X
- Sun Y
- Publication year
- Publication venue
- Signal transduction and targeted therapy
External Links
Snippet
Cancers are highly complex diseases that are characterized by not only the overgrowth of malignant cells but also an altered immune response. The inhibition and reprogramming of the immune system play critical roles in tumor initiation and progression. Immunotherapy …
- 206010028980 Neoplasm 0 title abstract description 121
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Wang et al. | Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response | |
Gaynor et al. | Immune checkpoint inhibitors: Key trials and an emerging role in breast cancer | |
US11944647B2 (en) | Articles of manufacture and methods for treatment using adoptive cell therapy | |
Khair et al. | Combining immune checkpoint inhibitors: established and emerging targets and strategies to improve outcomes in melanoma | |
Osipov et al. | From immune checkpoints to vaccines: The past, present and future of cancer immunotherapy | |
Khalil et al. | The future of cancer treatment: immunomodulation, CARs and combination immunotherapy | |
Wang et al. | Immune checkpoint blockade and its combination therapy with small-molecule inhibitors for cancer treatment | |
Pianko et al. | Immune checkpoint blockade for hematologic malignancies: a review | |
Mahoney et al. | Combination cancer immunotherapy and new immunomodulatory targets | |
Melaiu et al. | News on immune checkpoint inhibitors as immunotherapy strategies in adult and pediatric solid tumors | |
Ribas | Clinical development of the anti–CTLA-4 antibody tremelimumab | |
AU2013289967B2 (en) | Toxicity management for anti-tumor activity of CARs | |
US20190358262A1 (en) | Methods for modulation of car-t cells | |
CN111727373A (en) | Chimeric antigen receptor targeting BCMA and uses thereof | |
Honeychurch et al. | Immuno-regulatory antibodies for the treatment of cancer | |
CN110691795A (en) | Compositions comprising anti-LAG 3 antibodies, PD-1 pathway inhibitors, and immunotherapeutic agent combinations | |
Jackson et al. | Targeting CD8+ T-cell tolerance for cancer immunotherapy | |
Borrie et al. | T Lymphocyte–Based Cancer Immunotherapeutics | |
Wang et al. | The expression and immunoregulation of immune checkpoint molecule VISTA in autoimmune diseases and cancers | |
Haddad et al. | Resistance to immune checkpoint blockade: Mechanisms, counter-acting approaches, and future directions | |
Yu et al. | Harnessing the immune system by targeting immune checkpoints: Providing new hope for Oncotherapy | |
Mejía-Guarnizo et al. | The role of immune checkpoints in antitumor response: a potential antitumor immunotherapy | |
Liu et al. | Immune checkpoint inhibitors for multiple myeloma immunotherapy | |
Peng et al. | A narrative review of immune checkpoint mechanisms and current immune checkpoint therapy | |
US20220008465A1 (en) | Methods of dosing engineered t cells for the treatment of b cell malignancies |