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Thomas et al., 2013 - Google Patents

An optimized workflow for improved gene expression profiling for formalin-fixed, paraffin-embedded tumor samples

Thomas et al., 2013

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Document ID
14701826927012620134
Author
Thomas M
Poignée-Heger M
Weisser M
Wessner S
Belousov A
Publication year
Publication venue
Journal of clinical bioinformatics

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Snippet

Background Whole genome microarray gene expression profiling is the 'gold standard'for the discovery of prognostic and predictive genetic markers for human cancers. However, suitable research material is lacking as most diagnostic samples are preserved as formalin …
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6883Hybridisation probes for diseases caused by alterations of genetic material
    • C12Q1/6886Hybridisation probes for diseases caused by alterations of genetic material for cancer
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    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay
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    • G01N33/57407Specifically defined cancers
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