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Li et al., 2004 - Google Patents

Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family

Li et al., 2004

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Document ID
1478062123894069143
Author
Li Y
Nowotny P
Holmans P
Smemo S
Kauwe J
Hinrichs A
Tacey K
Doil L
Van Luchene R
Garcia V
Rowland C
Schrodi S
Leong D
Gogic G
Chan J
Cravchik A
Ross D
Lau K
Kwok S
Chang S
Catanese J
Sninsky J
White T
Hardy J
Powell J
Lovestone S
Morris J
Thal L
Owen M
Williams J
Goate A
Grupe A
Publication year
Publication venue
Proceedings of the National Academy of Sciences

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Snippet

Although several genes have been implicated in the development of the early-onset autosomal dominant form of Alzheimer's disease (AD), the genetics of late-onset AD (LOAD) is complex. Loci on several chromosomes have been linked to the disease, but so far only …
Continue reading at www.pnas.org (HTML) (other versions)

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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Hybridisation probes
    • C12Q1/6883Hybridisation probes for diseases caused by alterations of genetic material
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    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving viable micro-organisms
    • C12Q1/025Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving viable micro-organisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

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