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Bernstein et al., 2015 - Google Patents

TALE-mediated epigenetic suppression of CDKN2A increases replication in human fibroblasts

Bernstein et al., 2015

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Document ID
14745908276489174359
Author
Bernstein D
Le Lay J
Ruano E
Kaestner K
et al.
Publication year
Publication venue
The Journal of clinical investigation

External Links

Snippet

Current strategies to alter disease-associated epigenetic modifications target ubiquitously expressed epigenetic regulators. This approach does not allow specific genes to be controlled in specific cell types; therefore, tools to selectively target epigenetic modifications …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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