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Bos et al., 2008 - Google Patents

Balancing between antitumor efficacy and autoimmune pathology in T-cell–mediated targeting of carcinoembryonic antigen

Bos et al., 2008

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Document ID
14670585336271424044
Author
Bos R
van Duikeren S
Morreau H
Franken K
Schumacher T
Haanen J
van der Burg S
Melief C
Offringa R
Publication year
Publication venue
Cancer research

External Links

Snippet

Carcinoembryonic antigen (CEA) is intensively studied as a potential target for immunotherapy of colorectal cancers. Although overexpressed by tumors, CEA is also expressed in normal tissues, raising questions about the feasibility and safety of CEA …
Continue reading at www.academia.edu (PDF) (other versions)

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    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5152—Tumor cells
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