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Park et al., 2015 - Google Patents

Enhanced BBB permeability of osmotically active poly (mannitol-co-PEI) modified with rabies virus glycoprotein via selective stimulation of caveolar endocytosis for …

Park et al., 2015

Document ID
1430983319893879375
Author
Park T
Singh B
Li H
Lee J
Kang S
Choi Y
Cho C
Publication year
Publication venue
Biomaterials

External Links

Snippet

RNA interference (RNAi) holds one of the promising tools for Alzheimer's disease (AD) treatment by directly arresting the causative genes. For successful RNAi therapeutics for AD, limited access of therapeutic genes to the brain needs to be overcome by developing siRNA …
Continue reading at www.sciencedirect.com (other versions)

Classifications

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    • A61K47/48238—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the modifying agent being a protein, peptide, polyamino acid
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    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
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