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Mertz et al., 1939 - Google Patents

Inactivation of Prothrombin by Purified Thrombin Solutions.

Mertz et al., 1939

Document ID
14392876659493242383
Author
Mertz E
Seegers W
Smith H
Publication year
Publication venue
Proceedings of the Society for Experimental Biology and Medicine

External Links

Snippet

Evidence is presented to show that solutions of purified thrombin contain a substance which reacts slowly with prothrombin, causing inactivation of the latter. The destructive agent is not present in the calcium, prothrombin, or thromboplastin solutions from which the thrombin is …
Continue reading at journals.sagepub.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases Endopeptidases (3.4.21-3.4.25) derived from animal tissue

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