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Wang et al., 2018 - Google Patents

Activating autophagy enhanced the antitumor effect of antibody drug conjugates rituximab-monomethyl auristatin E

Wang et al., 2018

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Document ID
14287883999125838348
Author
Wang Y
Zhang X
Fan J
Chen W
Luan J
Nan Y
Wang S
Chen Q
Zhang Y
Wu Y
Ju D
Publication year
Publication venue
Frontiers in Immunology

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Background Antibody drug conjugate (ADC) showed potent therapeutic efficacy in several types of cancers. The role of autophagy in antitumor effects of ADC remains unclear. Methods In this study, the ADC, Rituximab-monomethyl auristatin E (MMAE) with a Valine …
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