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Collins et al., 1998 - Google Patents

Positional cloning of ZNF 217 and NABC 1: genes amplified at 20q13. 2 and overexpressed in breast carcinoma

Collins et al., 1998

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Document ID
14125587423895955635
Author
Collins C
Rommens J
Kowbel D
Godfrey T
Tanner M
Hwang S
Polikoff D
Nonet G
Cochran J
Myambo K
Jay K
Froula J
Cloutier T
Kuo W
Yaswen P
Dairkee S
Giovanola J
Hutchinson G
Isola J
Kallioniemi O
Palazzolo M
Martin C
Ericsson C
Pinkel D
Albertson D
Li W
Gray J
Publication year
Publication venue
Proceedings of the National Academy of Sciences

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We report here the molecular cloning of an≈ 1-Mb region of recurrent amplification at 20q13. 2 in breast cancer and other tumors and the delineation of a 260-kb common region of amplification. Analysis of the 1-Mb region produced evidence for five genes, ZNF217 …
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Hybridisation probes
    • C12Q1/6883Hybridisation probes for diseases caused by alterations of genetic material
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    • C12Q1/6802General aspects
    • C12Q1/6809Sequence identification involving differential detection
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