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Okabe et al., 2008 - Google Patents

Synergistic antitumor effect of S-1 and the epidermal growth factor receptor inhibitor gefitinib in non-small cell lung cancer cell lines: role of gefitinib-induced down …

Okabe et al., 2008

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Document ID
14171936245944818424
Author
Okabe T
Okamoto I
Tsukioka S
Uchida J
Iwasa T
Yoshida T
Hatashita E
Yamada Y
Satoh T
Tamura K
Fukuoka M
Nakagawa K
Publication year
Publication venue
Molecular cancer therapeutics

External Links

Snippet

Somatic mutations in the epidermal growth factor receptor (EGFR) gene are associated with the therapeutic response to EGFR tyrosine kinase inhibitors (TKI) in patients with advanced non-small cell lung cancer (NSCLC). The response rate to these drugs remains low …
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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