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Krajcer et al., 2023 - Google Patents

Strategies increasing the effectiveness of temozolomide at various levels of anti-GBL therapy

Krajcer et al., 2023

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Document ID
13913762093116156370
Author
Krajcer A
Grzywna E
Lewandowska-Łańcucka J
Publication year
Publication venue
Biomedicine & Pharmacotherapy

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Snippet

Glioblastoma (GBL) is the most common (60–70% of primary brain tumours) and the most malignant of the glial tumours. Although current therapies remain palliative, they have been proven to prolong overall survival. Within an optimal treatment regimen (incl. surgical …
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
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