[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Haeger et al., 2018 - Google Patents

Epithelial heparan sulfate contributes to alveolar barrier function and is shed during lung injury

Haeger et al., 2018

View PDF @Full View
Document ID
139435940665842842
Author
Haeger S
Liu X
Han X
McNeil J
Oshima K
McMurtry S
Yang Y
Ouyang Y
Zhang F
Nozik-Grayck E
Zemans R
Tuder R
Bastarache J
Linhardt R
Schmidt E
Publication year
Publication venue
American journal of respiratory cell and molecular biology

External Links

Snippet

The lung epithelial glycocalyx is a carbohydrate-enriched layer lining the pulmonary epithelial surface. Although epithelial glycocalyx visualization has been reported, its composition and function remain unknown. Using immunofluorescence and mass …
Continue reading at www.atsjournals.org (PDF) (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans

Similar Documents

Publication Publication Date Title
Haeger et al. Epithelial heparan sulfate contributes to alveolar barrier function and is shed during lung injury
Wu et al. Inhibition of alveolar macrophage pyroptosis reduces lipopolysaccharide-induced acute lung injury in mice
Qiao et al. Uncoupling DNA damage from chromatin damage to detoxify doxorubicin
Chignalia et al. The glycocalyx and trauma: a review
Chrysanthopoulou et al. Neutrophil extracellular traps promote differentiation and function of fibroblasts
Wang et al. Empagliflozin ameliorates diabetic cardiomyopathy via attenuating oxidative stress and improving mitochondrial function
Kanabar et al. Some structural determinants of the antiproliferative effect of heparin‐like molecules on human airway smooth muscle
Santos et al. Time course of lung parenchyma remodeling in pulmonary and extrapulmonary acute lung injury
Dechert et al. Hyaluronan in human acute and chronic dermal wounds
Zhong et al. Protein S protects against podocyte injury in diabetic nephropathy
Magnani et al. Glycomimetic drugs-a new source of therapeutic opportunities
Zhang et al. Hydrogen sulfide restores sevoflurane postconditioning mediated cardioprotection in diabetic rats: Role of SIRT1/Nrf2 signaling‐modulated mitochondrial dysfunction and oxidative stress
Lee et al. Mitochondrial DNA damage initiates acute lung injury and multi-organ system failure evoked in rats by intra-tracheal pseudomonas aeruginosa
Kitzmiller et al. Activation of AMP-activated protein kinase by A769662 ameliorates sepsis-induced acute lung injury in adult mice
Cervin et al. Effects of long‐term clarithromycin treatment on lavage‐fluid markers of inflammation in chronic rhinosinusitis
Markart et al. Safety and tolerability of inhaled heparin in idiopathic pulmonary fibrosis
Wijnhoven et al. In vivo degradation of heparan sulfates in the glomerular basement membrane does not result in proteinuria
Weidenfeld et al. Shedding first light on the alveolar epithelial glycocalyx
Urban et al. Colivelin, a synthetic derivative of humanin, ameliorates endothelial injury and glycocalyx shedding after sepsis in mice
Kelly et al. Heparan sulfate, including that in Bruch’s membrane, inhibits the complement alternative pathway: implications for age-related macular degeneration
Pescosolido et al. Trabecular meshwork in normal and pathological eyes
Ferrer-Gómez et al. Late cardiac pathology in severe covid-19. A postmortem series of 30 patients
Johansson et al. Ethyl pyruvate modulates acute inflammatory reactions in human endothelial cells in relation to the NF‐κB pathway
Pfeifer et al. Role of hemorrhage in the induction of systemic inflammation and remote organ damage: Analysis of combined pseudo‐fracture and hemorrhagic shock
Contessotto et al. Reproducing extracellular matrix adverse remodelling of non-ST myocardial infarction in a large animal model