Kurkuri et al., 2011 - Google Patents
Plasma functionalized PDMS microfluidic chips: towards point-of-care capture of circulating tumor cellsKurkuri et al., 2011
- Document ID
- 13832227634204362926
- Author
- Kurkuri M
- Al-Ejeh F
- Shi J
- Palms D
- Prestidge C
- Griesser H
- Brown M
- Thierry B
- Publication year
- Publication venue
- Journal of Materials Chemistry
External Links
Snippet
The main challenge in the isolation of circulating tumor cells (CTCs) resides in their extreme rarity in blood. Here we report on the design of efficient and disposable microfluidic CTC capture devices based on the plasma functionalization of PDMS and its subsequent …
- 239000004205 dimethyl polysiloxane 0 title abstract description 84
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/543—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Kurkuri et al. | Plasma functionalized PDMS microfluidic chips: towards point-of-care capture of circulating tumor cells | |
| Yu et al. | Flow-through functionalized PDMS microfluidic channels with dextran derivative for ELISAs | |
| Gervais et al. | Toward one-step point-of-care immunodiagnostics using capillary-driven microfluidics and PDMS substrates | |
| An et al. | Electrochemical biosensor for cancer cell detection based on a surface 3D micro-array | |
| Kwon et al. | Label-free, microfluidic separation and enrichment of human breast cancer cells by adhesion difference | |
| CN202066861U (en) | Special microfluidic chip used for diagnosing lung cancer rapidly | |
| JP2021041217A (en) | Polymer microfiltration devices, methods of manufacturing the same and the uses of the microfiltration devices | |
| US20090188864A1 (en) | Method and apparatus for microfiltration to perform cell separation | |
| WO2010108003A2 (en) | Device for capturing circulating cells | |
| Arakawa et al. | High-throughput single-cell manipulation system for a large number of target cells | |
| WO2018152296A1 (en) | Enhanced sensitivity and specificity for point-of-care (poc) micro biochip | |
| Liu et al. | Evaluation of microfluidic ceiling designs for the capture of circulating tumor cells on a microarray platform | |
| US11571695B2 (en) | Fluidic device and method for separating biomolecules | |
| Li et al. | On-chip selective capture of cancer cells and ultrasensitive fluorescence detection of survivin mRNA in a single living cell | |
| Thierry et al. | Herceptin functionalized microfluidic polydimethylsiloxane devices for the capture of human epidermal growth factor receptor 2 positive circulating breast cancer cells | |
| CN201421455Y (en) | Special micro-fluidic chip for syphilis diagnosis | |
| Liu et al. | Photografted poly (methyl methacrylate)-based high performance protein microarray for hepatitis B virus biomarker detection in human serum | |
| US11549946B2 (en) | Method for detecting cholangiocarcinoma cells | |
| CN113663747A (en) | High-dynamic-range multiple digital PCR chip and preparation method thereof | |
| CN201449391U (en) | Syphilis diagnosing device containing electrodes covered by gold colloid antigenic sensitive films | |
| CN112011435A (en) | Microfluidic system for accurately capturing circulating tumor cells and preparation method thereof | |
| Guan et al. | Non-invasive detection of bladder cancer via microfluidic immunoassay of the protein biomarker NMP22 | |
| CN202083692U (en) | Microfluidic chip specially used for gastric cancer diagnosis | |
| Roh et al. | Phosphorylcholine-based encoded hydrogel microparticles with enhanced fouling resistance for multiplex immunoassays | |
| US20230037522A1 (en) | Microfluidic device for detection of analytes |