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D’Arcy et al., 2019 - Google Patents

Development of a synthetic 3-ketosteroid Δ1-dehydrogenase for the generation of a novel catabolic pathway enabling cholesterol degradation in human cells

D’Arcy et al., 2019

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Document ID
1270692797795596401
Author
D’Arcy B
Swingle M
Schambeau L
Pannell L
Prakash A
Honkanen R
Publication year
Publication venue
Scientific Reports

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Snippet

Cholesterol is an essential component of membranes, which is acquired by cells via receptor-mediated endocytosis of lipoproteins or via de novo synthesis. In specialized cells, anabolic enzymes metabolize cholesterol, generating steroid hormones or bile acids …
Continue reading at www.nature.com (HTML) (other versions)

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