[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Abdul Qayum et al., 2019 - Google Patents

The Il9 CNS-25 regulatory element controls mast cell and basophil IL-9 production

Abdul Qayum et al., 2019

View HTML
Document ID
12083783484091816484
Author
Abdul Qayum A
Koh B
Martin R
Kenworthy B
Kharwadkar R
Fu Y
Wu W
Conrad D
Kaplan M
Publication year
Publication venue
The Journal of Immunology

External Links

Snippet

IL-9 is an important mediator of allergic disease that is critical for mast cell–driven diseases. IL-9 is produced by many cell types, including T cells, basophils, and mast cells. Yet, how IL- 9 is regulated in mast cells or basophils is not well characterized. In this report, we tested the …
Continue reading at www.ncbi.nlm.nih.gov (HTML) (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Similar Documents

Publication Publication Date Title
Guedan et al. Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability
Ebbo et al. Innate lymphoid cells: major players in inflammatory diseases
Klebanoff et al. Retinoic acid controls the homeostasis of pre-cDC–derived splenic and intestinal dendritic cells
Rochman et al. TSLP signaling in CD4+ T cells programs a pathogenic T helper 2 cell state
Abdul Qayum et al. The Il9 CNS-25 regulatory element controls mast cell and basophil IL-9 production
Mashiko et al. Human mast cells are major IL-22 producers in patients with psoriasis and atopic dermatitis
Ayano et al. Increased CD226 expression on CD8+ T cells is associated with upregulated cytokine production and endothelial cell injury in patients with systemic sclerosis
Kawabe et al. Homeostatic proliferation of naive CD4+ T cells in mesenteric lymph nodes generates gut-tropic Th17 cells
MacDonald et al. Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10
Rezende et al. Identification and characterization of latency-associated peptide-expressing γδ T cells
Grau et al. Antigen-induced but not innate memory CD8 T cells express NKG2D and are recruited to the lung parenchyma upon viral infection
Schaller et al. Epigenetic regulation of IL-12-dependent T cell proliferation
Fang et al. The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age
Rincon et al. Selective accumulation of Th2-skewing immature erythroid cells in developing neonatal mouse spleen
Nieminen et al. Dendritic cells from Crohn’s disease patients show aberrant STAT1 and STAT3 signaling
Roberts et al. MicroRNA-142 critically regulates group 2 innate lymphoid cell homeostasis and function
Kawabe et al. Redefining the foreign antigen and self-driven memory CD4+ T-cell compartments via transcriptomic, phenotypic, and functional analyses
Yang et al. MicroRNA-10a negatively regulates CD4+ T cell IL-10 production through suppression of Blimp1
Suzuki et al. Essential role for CD30-Transglutaminase 2 axis in memory Th1 and Th17 cell generation
Nelles et al. Murine splenic CD4+ T cells, induced by innate immune cell interactions and secreted factors, develop antileukemia cytotoxicity
Venkatasubramanian et al. TOLLIP optimizes dendritic cell maturation to lipopolysaccharide and Mycobacterium tuberculosis
Yokomizo-Nakano et al. Exposure to microbial products followed by loss of Tet2 promotes myelodysplastic syndrome via remodeling HSCs
Olivier et al. Plasticity of migrating CD1b+ and CD1b-lymph dendritic cells in the promotion of Th1, Th2 and Th17 in response to Salmonella and helminth secretions
Budeus et al. Human neonatal B cell immunity differs from the adult version by conserved Ig repertoires and rapid, but transient response dynamics
Kamii et al. IL-27 regulates the differentiation of follicular helper NKT cells via metabolic adaptation of mitochondria