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Louros et al., 2020 - Google Patents

Structure-based machine-guided mapping of amyloid sequence space reveals uncharted sequence clusters with higher solubilities

Louros et al., 2020

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Document ID
118741150534231831
Author
Louros N
Orlando G
De Vleeschouwer M
Rousseau F
Schymkowitz J
Publication year
Publication venue
Nature communications

External Links

Snippet

The amyloid conformation can be adopted by a variety of sequences, but the precise boundaries of amyloid sequence space are still unclear. The currently charted amyloid sequence space is strongly biased towards hydrophobic, beta-sheet prone sequences that …
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