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Gaál et al., 1998 - Google Patents

Low toxicity and high antitumour activity of daunomycin by conjugation to an immunopotential amphoteric branched polypeptide

Gaál et al., 1998

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Document ID
11714934658763094547
Author
Gaál D
Hudecz F
Publication year
Publication venue
European journal of Cancer

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Snippet

The acid labile derivative of Daunomycin cis-aconityl Daunomycin (cAD), was coupled to an amphoteric polypeptide, poly [Lys-(Glui-dl-Alam)](EAK), which was selected for conjugation on the basis of its pharmacological and immunological properties. The systemic toxicity of …
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