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Gerrits et al., 1997 - Google Patents

Topoisomerase I inhibitors: the relevance of prolonged exposure for present clinical development

Gerrits et al., 1997

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Document ID
11744646741347016673
Author
Gerrits C
De Jonge M
Schellens J
Stoter G
Verweij J
Publication year
Publication venue
British journal of cancer

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Snippet

Topoisomerase I inhibitors constitute a new class of anti-cancer agents. Recently, topotecan and irinotecan were registered for clinical use in ovarian cancer and colorectal cancer respectively. Cytotoxicity of topoisomerase I inhibitors is S-phase specific, and in vitro and in …
Continue reading at www.ncbi.nlm.nih.gov (PDF) (other versions)

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