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Huffman et al., 1972 - Google Patents

Stereoselective nonannelation synthesis of eudalene sesquiterpenes

Huffman et al., 1972

Document ID
11564147129416530178
Author
Huffman J
Mole M
Publication year
Publication venue
The Journal of Organic Chemistry

External Links

Snippet

A new stereoselective synthetic approach to the eudalene sesquiterpenes has been devised which does not utilize theRobinson annelation sequence. Clemmensen reduction of 5- methoxy-l-tetralonecarboxylic acid (4) gives 8-methoxytetralin-2-carboxylic acid (5), which …
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    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
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    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
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    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
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